Quarterbacks: Start 'Em, Sit 'Em
Baker Mayfield (Tampa Bay Buccaneers at Detroit Lions)
Mayfield was electric in Week 1, tossing 4 touchdowns with zero turnovers. Now traveling to Ford Field for an indoor shootout against Detroit, game flow strongly favors 35+ passing attempts. The Lions secondary allowed over 300 passing yards to Matthew Stafford; Mayfield and Mike Evans will exploit single high safety looks.
Deshaun Watson (Cleveland Browns at Jacksonville Jaguars)
Watson struggled immensely against Dallas, taking 6 sacks and averaging under 4.0 yards per attempt. With offensive line injuries mounting, Jacksonville's pass rush duo of Josh Allen and Travon Walker creates a severe turnover hazard. Keep Watson on the bench.
Running Backs: Start 'Em, Sit 'Em
Jordan Mason (San Francisco 49ers at Minnesota Vikings)
With Christian McCaffrey shifted to IR, Mason is an undeniable RB1 start. He handled 28 carries for 147 yards and a touchdown in Week 1. San Francisco's offensive scheme guarantees 18+ high-value touches in what projects as a multi-touchdown scoring environment.
D'Andre Swift (Chicago Bears at Houston Texans)
Swift managed just 30 yards on 10 carries against Tennessee while splitting snaps with Travis Homer and Khalil Herbert. Houston's defense smothered opposing rushers in Week 1, making Swift a touchdown-dependent RB3 on Sunday Night Football.
Wide Receivers: Start 'Em, Sit 'Em
Jameson Williams (Detroit Lions vs. Tampa Bay Buccaneers)
Williams enjoyed a true third-year breakout in Week 1, earning 9 targets for 121 yards and a touchdown, plus a 15-yard designed rush. Tampa Bay plays heavy Cover-3 zone, leaving deep boundary seams open for Williams' track speed.
Courtland Sutton (Denver Broncos vs. Pittsburgh Steelers)
Sutton faces shadow coverage from Steelers cornerback Joey Porter Jr., who held Kirk Cousins' perimeter receivers in check in Week 1. With rookie Bo Nix adjusting to NFL blitz schemes, Sutton lacks the volume to justify a WR2/3 start.
Tight Ends: Start 'Em, Sit 'Em
Isaiah Likely (Baltimore Ravens vs. Las Vegas Raiders)
Likely led all tight ends in fantasy points in Week 1 with 9 catches on 12 targets for 111 yards and a touchdown. The Raiders linebackers struggle in slot zone coverage; Likely has graduated to must-start status across all 12-team leagues.
Prepare Your Complete Week 2 Roster
Frequently Asked Questions
What if a player is listed as Questionable for the Sunday Night Game?
Always have a pivot option ready from the same late window or Monday Night Football game. If your starter is a game-time decision on Sunday night, benching them for a guaranteed 1:00 PM starter is frequently the lower-variance play.